Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Jul 15;182(1):245-7.
doi: 10.1042/bj1820245.

Endocytosis of beta-N-acetylglucosaminidase from sections of mucolipidosis-II and-III fibroblasts by non-parenchymal rat liver cells

K Ullrich, K von Figura

Endocytosis of beta-N-acetylglucosaminidase from sections of mucolipidosis-II and-III fibroblasts by non-parenchymal rat liver cells

K Ullrich et al. Biochem J. .

Abstract

beta-N-Acetylglucosaminidase isolated from the secretions of fibroblasts of mucolipidosis-II and -III patients is internalized by cultured non-parenchymal rat liver cells. The rate of endocytosis compared with that of beta-N-acetylglucosaminidase from control fibroblasts was 11 and 19% for the enzyme from mucolipidosis-II and -III patients respectively. The inhibition of endocytosis by mannan indicates that the beta-N-acetylglucosaminidase from mucolipidosis-II and -III patients is recognized by cell-surface receptors specific for mannose.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Biochem J. 1979 May 15;180(2):413-9 - PubMed
    1. Methods Cell Biol. 1976;13:29-83 - PubMed
    1. Proc Natl Acad Sci U S A. 1977 May;74(5):2026-30 - PubMed
    1. Eur J Biochem. 1979 Mar;94(2):347-54 - PubMed
    1. Hoppe Seylers Z Physiol Chem. 1978 Nov;359(11):1591-8 - PubMed