doi: 10.1128/jb.96.5.1488-1499.1968.
Genetic control of the beta-ketoadipate pathway in Pseudomonas aeruginosa
- PMID: 4973125
- PMCID: PMC315200
- DOI: 10.1128/jb.96.5.1488-1499.1968
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Genetic control of the beta-ketoadipate pathway in Pseudomonas aeruginosa
J Bacteriol.
1968 Nov.
Abstract
The regulation and genetic control of the beta-ketoadipate pathway in Pseudomonas aeruginosa were investigated. The pattern of enzyme induction is apparently the same as in P. putida. Mutants were obtained for all but 1 of the 11 structural genes; the proximity of these genes on the chromosome was examined by transduction of the mutants with phage F116. If a group of enzymes was induced by the same compounds, the corresponding genes were closely clustered. Surprisingly, some locispecifying enzymes not sharing a common inducer were also clustered. It is suggested that this latter finding may indicate a degree of chromosomal specialization.
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