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. 1970 Sep 12;3(5723):624-5.
doi: 10.1136/bmj.3.5723.624.

Changes in gut flora after cephalexin treatment

H Gaya, P I Adnitt, P Turner

Changes in gut flora after cephalexin treatment

H Gaya et al. Br Med J. .

Abstract

Eighteen patients with urinary tract infection were treated with cephalexin orally. Absorption was variable, between 29 and 89% of the total daily dose being excreted in the urine in 24 hours. A significant number of patients became faecal carriers of Pseudomonas aeruginosa compared with a control group who received no antibiotics. Four of the cephalexin-treated patients acquired a strain of Ps. aeruginosa known to be present in food from the hospital diet kitchen and one developed a urinary tract infection with this strain.

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