Anti-thymocyte serum effects on Plasmodium berghei infection in rats
- PMID: 4991884
- PMCID: PMC1455636
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Anti-thymocyte serum effects on Plasmodium berghei infection in rats
Immunology.
1970 Nov.
Abstract
Rabbit anti-rat thymocyte serum (ATS) virtually abolished the innate resistance mechanism(s) of rats of different ages to primary infection with Plasmodium berghei. ATS apparently produced its immunosuppressant effect without arresting humoral antibody production as judged by agar-gel double diffusion tests. These results, when considered together with those of other workers, suggest that cell-mediated immunity is substantially involved in resistance to P. berghei.
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