Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Aug 1;4(4):271-5.
doi: 10.1007/BF00304882.

The mechanism of the localization of 67gallium citrate in experimental abscesses

P A Hammersley, D M Taylor

The mechanism of the localization of 67gallium citrate in experimental abscesses

P A Hammersley et al. Eur J Nucl Med. .

Abstract

67Ga accumulation in turpentine-induced abscesses, from 5 h to 20 days old, in the rat has been investigated, and the results indicate that this is dependent on polymorphonuclear leukocyte (PMN) infiltration of the inflamed site. 67Ga concentration 24 h after injection correlates well with the activities of the lysosomal enzymes, aryl sulphatase and beta-glucuronidase, P less than 0.001, and with the DNA content of the tissue. There is no direct relationship with the rate of DNA synthesis. The mechanism of lysosomal incorporation into PMNs is consistent with the factors involved in 67Ga uptake into tumours and normal tissues.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Nucl Med (Stuttg). 1974 May 31;13(1):72-84 - PubMed
    1. J Nucl Med. 1978 Mar;19(3):292-4 - PubMed
    1. J Natl Cancer Inst. 1971 May;46(5):941-52 - PubMed
    1. Cancer Res. 1975 May;35(5):1154-8 - PubMed
    1. J Nucl Med. 1975 Nov;16(11):990-2 - PubMed