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. 1971 May 14;172(3984):727-8.
doi: 10.1126/science.172.3984.727.

Galactosemia: evidence for a structural gene mutation

Galactosemia: evidence for a structural gene mutation

T A Tedesco et al. Science. .

Abstract

Identical immunoprecipitin reactions appeared in double immunodiffusion between rabbit anltibodies to human galactose-1-phosphate uridyl transferase and red cell preparations from both normal and galactosemic individuals. The galactosemic erythrocyte preparations quantitatively absorbed the antiboy that immunoprecipitates enzymatically active galactose-1-phosphate uridyl transferase.

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