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. 1971 Jul 2;173(3991):62-4.
doi: 10.1126/science.173.3991.62.

Teratogenic effects of a chelating agent and their prevention by zinc

H Swenerton, L S Hurley

Teratogenic effects of a chelating agent and their prevention by zinc

H Swenerton et al. Science. .

Abstract

Ingestion of a chelating agent (ethylenediaminetetraacetic acid) by female rats during pregnancy impaired reproduction and resulted in congenitally malformed young. When ethylenediaminetetraacetic acid was fed from days 6 to 21 of gestation, all of the full-term young had gross congenital malformations. These effects were prevented by simultaneous supplementation with 1000 parts per million of dietary zinc.

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