Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1971 Apr;7(4):515-23.
doi: 10.1128/JVI.7.4.515-523.1971.

Abortive infection of sporulating Bacillus subtilis 168 by phi 2 bacteriophage

J Ito, J Spizizen

Abortive infection of sporulating Bacillus subtilis 168 by phi 2 bacteriophage

J Ito et al. J Virol. 1971 Apr.

Abstract

Bacteriophage phi2 is unable to replicate in Bacillus subtilis 168. Although some phage deoxyribonucleic acid (DNA) synthesis can occur, the DNA made is not biologically active and sedimentation analysis reveals that it is smaller in size than that of mature DNA or DNA isolated from phi2-infected permissive hosts. Messenger ribonucleic acid hybridizable with phi2 DNA is also synthesized in phi2-infected cells of 168. Mutants of 168 which are permissive hosts for phi2 have been isolated. These mutants are defective in sporulation and possess the phenotype of "early sporulation mutants." The majority map in two locations, one near the lys locus opposite the trp locus (spoA locus) and the other tightly linked to a phe locus.

PubMed Disclaimer

References

    1. Annu Rev Biochem. 1969;38:467-500 - PubMed
    1. Biochem Biophys Res Commun. 1966 Jun 13;23(5):641-6 - PubMed
    1. Nature. 1970 Aug 29;227(5261):906-9 - PubMed
    1. J Mol Biol. 1962 Nov;5:527-34 - PubMed
    1. J Appl Bacteriol. 1970 Mar;33(1):13-24 - PubMed

MeSH terms

LinkOut - more resources