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. 1971 Oct;68(10):2472-6.
doi: 10.1073/pnas.68.10.2472.

Evidence for position-effect suppression of the ribosomal RNA cistrons in Drosophila melanogaster

W K Baker

Evidence for position-effect suppression of the ribosomal RNA cistrons in Drosophila melanogaster

W K Baker. Proc Natl Acad Sci U S A. 1971 Oct.

Abstract

Unambiguous evidence is presented that two X-chromosome inversions produce lethality in X/O males because of position-effect suppression of genes in the basal heterochromatin. The data support the hypothesis that the ribosomal RNA cistrons are the genes suppressed. There is evidence for a region in the X basal heterochromatin that may act as a regulator of rDNA activity.

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