Restoration of the excitability of squid giant axon by tubulin-tyrosine ligase and microtubule proteins
- PMID: 500583
- DOI: 10.1093/oxfordjournals.jbchem.a132611
Restoration of the excitability of squid giant axon by tubulin-tyrosine ligase and microtubule proteins
Abstract
Membrane excitability of the squid giant axon was destroyed by perfusing with a medium containing 0.2 mM Ca ions that depolymerize microtubules. Restoration of the membrane excitability was achieved by perfusing the axon with a medium that contained purified tubulin-tyrosine ligase, tubulin, ATP, Mg2+, K+, cyclic AMP, and 300 K Protein.

