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. 1972 Jan 14;175(4018):187-9.
doi: 10.1126/science.175.4018.187.

Initiation of protein synthesis at an unusual position in an immunoglobulin gene?

O Smithies, M D Poulik

Initiation of protein synthesis at an unusual position in an immunoglobulin gene?

O Smithies et al. Science. .

Abstract

The amino acid sequence of urinary beta(2)-microglobulin has been partially determined and found to be related to the constant region of IgG immunoglobulin heavy chain. beta(2)-Microglobulin is present in normal individuals. Its gene may have evolved from an immunoglobulin gene by the use of an unusually located start signal for initiating synthesis of the polypeptide.

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