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. 1972 Feb;53(1):1-4.

Circulating endothelial cells and arterial endothelial mitosis in anaphylactic shock

H P Wright, N J Glacometti

Circulating endothelial cells and arterial endothelial mitosis in anaphylactic shock

H P Wright et al. Br J Exp Pathol. 1972 Feb.

Abstract

Sensitized guinea-pigs received a shocking dose of ovalbumin. Within 8 min endothelial cells ranging in numbers between 24·0 and 13·88/1000 leukocytes were recovered from the peripheral blood. Control animals had counts between 0·00 and 4·40. Subsequent injection of T-3H and autoradiographic study of Hautchen preparations of aortic endothelium showed a 3-fold increase in mitosis in the shocked animals when compared with controls. The increase in mitosis represents the repair process following endothelial distruction caused by anaphylactic shock.

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