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. 1972 Feb;35(1):77-80.
doi: 10.1136/jnnp.35.1.77.

H reflex studies in patients with Parkinson's disease

J G McLeod, J C Walsh

H reflex studies in patients with Parkinson's disease

J G McLeod et al. J Neurol Neurosurg Psychiatry. 1972 Feb.

Abstract

The H reflex was studied in 13 patients with Parkinson's disease, and the results compared with those obtained in 22 control subjects. Pairs of identical stimuli near threshold intensity were delivered and the unresponsive period and time course of recovery of the amplitude of the H reflex were determined. The duration of the unresponsive period was significantly shorter in the patients with Parkinson's disease. In 10 patients the studies were repeated after treatment with l-dopa for six months. There was a significant increase in the period of unresponsiveness of the H reflex after treatment. The findings suggest that there is an increase in alpha motoneurone excitability in Parkinson's disease, and that it is reduced by treatment with l-dopa.

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References

    1. Brain. 1967 Dec;90(4):887-96 - PubMed
    1. Science. 1965 Dec 10;150(3702):1472-5 - PubMed
    1. Arch Neurol. 1962 May;6:404-13 - PubMed
    1. J Neurol Neurosurg Psychiatry. 1960 May;23:99-118 - PubMed
    1. Arch Neurol. 1967 Apr;16(4):421-32 - PubMed

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