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. 1972 Aug 1;136(2):369-74.
doi: 10.1084/jem.136.2.369.

Brain-associated stem cell antigen: an antigen shared by brain and hemopoietic stem cells

E S Golub

Brain-associated stem cell antigen: an antigen shared by brain and hemopoietic stem cells

E S Golub. J Exp Med. .

Abstract

There is an antigen on mouse brain tissue which is shared by the hemopoietic colony-forming unit or stem cell of the mouse. Treatment of bone marrow or fetal liver cells with anti-brain antisera inhibits expression of colony-forming units. The anti-stem cell antibody is not absorbed by thymus cells and thus can be distinguished from the anti-thymocyte antibody which these antisera also contain.

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