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. 1972 Aug 1;136(2):375-80.
doi: 10.1084/jem.136.2.375.

Antibody-mediated suppression of grafted lymphoma cells. II. Participation of macrophages

H S Shin, N Kaliss, D Borenstein, M K Gately

Antibody-mediated suppression of grafted lymphoma cells. II. Participation of macrophages

H S Shin et al. J Exp Med. .

Abstract

Specific alloantibody admixed with a grafted murine lymphoma is suppressive of the graft in mice of the inbred strain native to the tumor. Suppressive capacity of the host is obviated in mice given 500 R whole body irradiation before tumor inoculation but is restored when normal peritoneal macrophages are admixed with the tumor-antibody inoculum. Other normal cell types admixed with the tumor-antibody inoculum are not effective in restoring suppressive capacity.

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References

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    1. Proc Soc Exp Biol Med. 1972 Feb;139(2):684-9 - PubMed