Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1972 Aug;12(8):948-59.
doi: 10.1016/S0006-3495(72)86136-8.

On the theory of ion transport across the nerve membrane. IV. Noise from the open-close kinetics of K + channels

T L Hill, Y D Chen

On the theory of ion transport across the nerve membrane. IV. Noise from the open-close kinetics of K + channels

T L Hill et al. Biophys J. 1972 Aug.

Abstract

The theoretical power density spectrum G(f) of fluctuations in the steady-state squid axon K(+) current in the 10(3) Hz region has been derived assuming that these are fluctuations in the number of open K(+) channels in the Hodgkin-Huxley (HH) model. Various modifications of the HH model were also studied. The results were negative in all cases when compared with experiment. This confirms the generally held view that the observed G(f) approximately 1/f is associated primarily with K(+) current through open K(+) channels and not with the open-close kinetics of these channels.

PubMed Disclaimer

References

    1. Acta Physiol Pharmacol Neerl. 1965-1966;13(4):373-466 - PubMed
    1. Biophys J. 1971 Feb;11(2):211-34 - PubMed
    1. Proc Natl Acad Sci U S A. 1971 Aug;68(8):1711-5 - PubMed
    1. Proc Natl Acad Sci U S A. 1971 Oct;68(10):2488-92 - PubMed
    1. J Physiol. 1952 Apr;116(4):473-96 - PubMed

LinkOut - more resources