doi: 10.1126/science.177.4048.534.
Facilitation of recovery by -methyl-p-tyrosine after lateral hypothalamic damage
- PMID: 5050488
- DOI: 10.1126/science.177.4048.534
Item in Clipboard
Facilitation of recovery by -methyl-p-tyrosine after lateral hypothalamic damage
Science.
.
Abstract
Rats with bilateral lateral hypothalamic lesions die of starvation in approximately 7 days after surgery. Rats that were treated with alpha-methyl-p-tyrosine for 3 days prior to lateral hypothalamic surgery spontaneously eat, drink, and gain weight after surgery. These data suggest that recovery of function after lateral hypothalamic damage involves denervation supersensitivity.
Similar articles
-
Facilitation of lateral hypothalamic recovery by postoperative administration of a-methyl-p-tyrosine.Brain Res. 1974 Jun 14;73(1):180-3. doi: 10.1016/0006-8993(74)91020-8. Brain Res. 1974. PMID: 4407398 No abstract available.
-
Effects of haloperidol, methyltyrosine and morphine on recovery from lesions of lateral hypothalamus.Pharmacol Biochem Behav. 1975 Sep-Oct;3(5):755-9. doi: 10.1016/0091-3057(75)90102-1. Pharmacol Biochem Behav. 1975. PMID: 1208617
-
Recovery of feeding and drinking by rats after intraventricular 6-hydroxydopamine or lateral hypothalamic lesions.Science. 1973 Nov 16;182(4113):717-20. doi: 10.1126/science.182.4113.717. Science. 1973. PMID: 4752211
-
Microdialysis studies of brain norepinephrine, serotonin, and dopamine release during ingestive behavior. Theoretical and clinical implications.Ann N Y Acad Sci. 1989;575:171-91; discussion 192-3. doi: 10.1111/j.1749-6632.1989.tb53242.x. Ann N Y Acad Sci. 1989. PMID: 2699187 Review.
-
Role of brain norepinephrine and serotonin in the tonic and phasic regulation of hypothalamic hypophyseal adrenal axis.Arch Int Pharmacodyn Ther. 1972 Apr;196:Suppl 196:205+. Arch Int Pharmacodyn Ther. 1972. PMID: 4342944 Review. No abstract available.
Cited by
-
Effects of alpha-methyl-p-tyrosine on morphine depnendence.Psychopharmacologia. 1973 Oct 15;32(4):365-71. doi: 10.1007/BF00429473. Psychopharmacologia. 1973. PMID: 4796836 No abstract available.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
