Efficacy of oxfendazole against naturally acquired gastro-intestinal nematode infestations in buffaloes in Egypt

Abstract

The benzimidazole anthelmintic, oxfendazole, was used as an oral suspension at 4.5 and 2.8 mg/kg to treat naturally infested indigenous buffaloes in Egypt. Worms of the genera Haemonchus, Cooperia, Trichostrongylus, Ostertagia, Chabertia and Oesophagostomum were identified in the animals prior to treatment. A 100% reduction in faecal egg counts was obtained at the 4.5 mg/kg level when compared to untreated control animals. Reductions in faecal egg counts greater than 90% were recorded at 2.8 mg/kg and these exceeded reductions obtained by drenching with the older benzimidazole anthelmintic, thiabendazole, at 67 and 111 mg/kg.