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. 1972 Mar 1;135(3):443-57.
doi: 10.1084/jem.135.3.443.

Viral and cellular surface antigens of murine leukemias and myelomas. Serological analysis by immunoelectron microscopy

T Aoki, T Takahashi

Viral and cellular surface antigens of murine leukemias and myelomas. Serological analysis by immunoelectron microscopy

T Aoki et al. J Exp Med. .

Abstract

IMMUNOELECTRON MICROSCOPY (IEM) OF MOUSE CELLS WHICH WERE PRODUCTIVELY INFECTED WITH MURINE LEUKEMIA VIRUS (MULV) YIELDED THE FOLLOWING CONCLUSIONS: See PDF for Structure With two exceptions, the alloantigens H-2, theta, Ly-A, and Ly-B were not present on complete or incomplete virions produced by cells bearing these antigens.The exceptions were H-2(k) (but not H-2(b)) and theta both appeared on only a minority of virions and never on more than a small part of the circumference. The incidental discovery of an additional envelope antigen on virions produced by a BALB/c mouse myeloma but lacking from passage A Gross virions distinguishes these two viruses as MuLV subtypes; it also illustrates that IEM can be applied as a primary tool for antigenic analysis, as well as for its usual purpose of finding out where antigens are situated.

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References

    1. Cancer Res. 1965 Jul;25(6):813-9 - PubMed
    1. Fed Proc. 1965 Sep-Oct;24(5):1009-17 - PubMed
    1. J Exp Med. 1966 Oct 1;124(4):753-72 - PubMed
    1. Proc R Soc Lond B Biol Sci. 1968 Jun 11;170(1019):175-93 - PubMed
    1. J Exp Med. 1968 Dec 1;128(6):1461-73 - PubMed