doi: 10.1128/am.23.1.72-77.1972.
Microbial degradation of sterols
- PMID: 5059623
- PMCID: PMC380279
- DOI: 10.1128/am.23.1.72-77.1972
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Microbial degradation of sterols
Appl Microbiol.
1972 Jan.
Abstract
A process is described for the microbial degradation of cholesterol and plant sterols, to produce androsta-1, 4-diene-3, 17-dione and androst-4-ene-3, 17-dione, by two newly isolated bacteria designated Mycobacterium sp. NRRL B-3683 and Mycobacterium sp. NRRL B-3805. These myocbacteria produce substantial amounts of 17-ketonic compounds without appreciable degradation of the steroid nucleus. No ring degradation inhibitory agents are necessary. The first microbiological production of 20alpha-hydroxymethylpregna-1, 4-dien-3-one is also reported.
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