Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1972 Jan;23(1):72-7.
doi: 10.1128/am.23.1.72-77.1972.

Microbial degradation of sterols

W J Marsheck, S Kraychy, R D Muir

Microbial degradation of sterols

W J Marsheck et al. Appl Microbiol. 1972 Jan.

Abstract

A process is described for the microbial degradation of cholesterol and plant sterols, to produce androsta-1, 4-diene-3, 17-dione and androst-4-ene-3, 17-dione, by two newly isolated bacteria designated Mycobacterium sp. NRRL B-3683 and Mycobacterium sp. NRRL B-3805. These myocbacteria produce substantial amounts of 17-ketonic compounds without appreciable degradation of the steroid nucleus. No ring degradation inhibitory agents are necessary. The first microbiological production of 20alpha-hydroxymethylpregna-1, 4-dien-3-one is also reported.

PubMed Disclaimer

References

    1. Steroids. 1966 May;7(5):429-32 - PubMed
    1. J Am Chem Soc. 1970 Apr 8;92(7):2161-3 - PubMed
    1. Angew Chem Int Ed Engl. 1970 May;9(5):321-32 - PubMed
    1. J Am Chem Soc. 1965 Mar 20;87:1387-8 - PubMed
    1. Steroids. 1968 Mar;11(3):401-13 - PubMed

LinkOut - more resources