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. 1972 Jan;23(1):88-90.
doi: 10.1128/am.23.1.88-90.1972.

In vitro evaluation of actinobolin as an antibiotic for the treatment of periodontal disease

P J Armstrong Jr, D E Hunt

In vitro evaluation of actinobolin as an antibiotic for the treatment of periodontal disease

P J Armstrong Jr et al. Appl Microbiol. 1972 Jan.

Abstract

Actinobolin was evaluated in vitro by a paper disc-agar diffusion method for inhibitory activity against mixed microbial cultures obtained from patients with periodontal disease and against pure bacterial cultures tentatively identified as strains of Bacteroides melaninogenicus, Fusobacterium fusiforme, Leptotrichia buccalis, and Veillonella parvula. Every culture tested was inhibited to some degree by actinobolin. These observations suggest that actinobolin may be effective in the treatment of periodontal disease.

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References

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    1. J Am Dent Assoc. 1969 Dec;79(6):1395-404 - PubMed
    1. J Dent Res. 1970 Jan-Feb;49(1):137-9 - PubMed
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