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Case Reports
. 1979 Oct;48(1):27-30.
doi: 10.1007/BF00691787.

Ultrastructure of neurofibrillary tangles in progressive supranuclear palsy

Case Reports

Ultrastructure of neurofibrillary tangles in progressive supranuclear palsy

S Yagishita et al. Acta Neuropathol. 1979 Oct.

Abstract

The fine structure of neurofibrillary tangles in the hippocampal gyrus, substantia nigra, pontine nuclei and locus coeruleus of the brain was postmortem studied in a case of progressive supranuclear palsy. Straight tubules and twisted tubules were observed in both the cortical and subcortical neurofibrillary tangles. Most tubules appeared separately in each neuron but a few straight tubules were mixed with the twisted tubules in the cortical tangles. The implication and possible significance of this findings are discussed.

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