doi: 10.1126/science.178.4056.56.
Evidence for the neutral hypothesis of protein polymorphism
- PMID: 5070515
- DOI: 10.1126/science.178.4056.56
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Evidence for the neutral hypothesis of protein polymorphism
Science.
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Abstract
Data for some 400 polymorphic proteins were examined with special reference to molecular evolution, by using a statistic that depends on neither mutation rate, population structure, nor other ecological factors. The result indicates that most of these polymorphisms are maintained in a population by mutation and random genetic drift.
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