The detection of fibrinogen-fibrin degradation products by means of a new antibody-coated latex particle
- PMID: 5076802
- PMCID: PMC477476
- DOI: 10.1136/jcp.25.8.680
The detection of fibrinogen-fibrin degradation products by means of a new antibody-coated latex particle
Abstract
A rapid slide test for the detection of degradation products of fibrinogen/fibrin (FDP) using a new antibody-coated latex particle is described. The latex particle has been specifically coated with antibody to fragments D and E. The latex agglutination test (Thrombo-Wellcotest) has been compared with the tanned red cell haemagglutination inhibition immunoassay (TRCHII) in 143 patients with a variety of clinical conditions. There is a high degree of agreement between the methods with a coefficient of correlation of 0.83. The method provides a rapid, simple screening test for fibrin degradation products.
Similar articles
-
Evaluation of a new anti-fibrinogen-coated latex particle agglutination test in the measurement of serum fibrin degradation products.Thromb Haemost. 1977 Apr 30;37(2):183-91. Thromb Haemost. 1977. PMID: 577622
-
Comparison of a direct latex-agglutination technic with the tanned red cell hemagglutination inhibition immunoassay (TRCHII) for semiquantitation of fibrinogen/fibrin degradation products.Am J Clin Pathol. 1976 Apr;65(4):528-32. Am J Clin Pathol. 1976. PMID: 1266814
-
A comparison between radioimmunoassay and other immunological techniques for the measurement of fibrinogen/fibrin degradation products in serum.Br J Haematol. 1975 Jun;30(2):145-9. doi: 10.1111/j.1365-2141.1975.tb00528.x. Br J Haematol. 1975. PMID: 1201206
-
[Detection of fibrinogen and fibrin degradation products (FDP) and its clinical significance].Nihon Rinsho. 1973 Apr;31(4):798-804. Nihon Rinsho. 1973. PMID: 4580396 Review. Japanese. No abstract available.
-
Monoclonal antibody-based plasma assays for fibrin(ogen) and derivatives, and their clinical relevance.Blood Coagul Fibrinolysis. 1990 Mar-Apr;1(1):91-111. doi: 10.1097/00001721-199003000-00012. Blood Coagul Fibrinolysis. 1990. PMID: 2102791 Review.
Cited by
-
Transport of urokinase across the intestinal tract of normal human subjects with stimulation of synthesis and/or release of urokinase-type proteins.J Clin Invest. 1985 Apr;75(4):1212-22. doi: 10.1172/JCI111818. J Clin Invest. 1985. PMID: 3921568 Free PMC article.
-
Enhanced antiplasmin activity in acute renal failure.Br Med J. 1975 Oct 25;4(5990):195-7. doi: 10.1136/bmj.4.5990.195. Br Med J. 1975. PMID: 1191995 Free PMC article.
-
Altered coagulation protein content after albumin resuscitation.Ann Surg. 1982 Aug;196(2):198-202. doi: 10.1097/00000658-198208000-00013. Ann Surg. 1982. PMID: 6807224 Free PMC article.
-
Disseminated intravascular coagulation in the pathogenesis of adult respiratory distress syndrome: 1. Clinical study.Jpn J Surg. 1977 Dec;7(4):217-22. doi: 10.1007/BF02469353. Jpn J Surg. 1977. PMID: 606892
-
The coagulopathy associated with aortic aneurysms.Postgrad Med J. 1977 Nov;53(625):668-71. doi: 10.1136/pgmj.53.625.668. Postgrad Med J. 1977. PMID: 593992 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources