Case Reports
doi: 10.1001/archneur.1979.00500470085019.
Trial of baclofen in amyotrophic lateral sclerosis
- PMID: 508132
- DOI: 10.1001/archneur.1979.00500470085019
Item in Clipboard
Case Reports
Trial of baclofen in amyotrophic lateral sclerosis
Arch Neurol.
1979 Nov.
Abstract
A trial of the antispastic drug baclofen was made in amyotrophic lateral sclerosis. Some patients noted reduction of tonus and spasticity; but others had no benefit, nor was the course of the disease altered by long-term administration of baclofen. No major side effects occurred.
Similar articles
-
A double-blind comparative trial of new muscle relaxant, tizanidine (DS 103-282), and baclofen in the treatment of chronic spasticity in multiple sclerosis.Curr Med Res Opin. 1981;7(6):374-83. Curr Med Res Opin. 1981. PMID: 7016449 Clinical Trial.
-
Baclofen, a new antispastic drug. A controlled, multicenter trial in patients with multiple sclerosis.Arch Neurol. 1977 Jul;34(7):422-8. doi: 10.1001/archneur.1977.00500190056008. Arch Neurol. 1977. PMID: 327987 Clinical Trial.
-
Controlled trial of thyrotropin releasing hormone in amyotrophic lateral sclerosis.Neurology. 1986 Feb;36(2):146-51. doi: 10.1212/wnl.36.2.146. Neurology. 1986. PMID: 3080694 Clinical Trial.
-
Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).Amyotroph Lateral Scler Other Motor Neuron Disord. 2003 Sep;4(3):191-206. Amyotroph Lateral Scler Other Motor Neuron Disord. 2003. PMID: 13129806 Review.
-
Misdiagnosis and missed diagnoses in patients with ALS.JAAPA. 2006 Jul;19(7):29-35. JAAPA. 2006. PMID: 16869150 Review. No abstract available.
Cited by
-
Gamma aminobutyric acid (GABA) modulators for amyotrophic lateral sclerosis/motor neuron disease.Cochrane Database Syst Rev. 2017 Jan 9;1(1):CD006049. doi: 10.1002/14651858.CD006049.pub2. Cochrane Database Syst Rev. 2017. PMID: 28067943 Free PMC article.
-
Longitudinal grey matter and metabolic contributions to cognitive changes in amyotrophic lateral sclerosis.Brain Commun. 2022 Sep 7;4(5):fcac228. doi: 10.1093/braincomms/fcac228. eCollection 2022. Brain Commun. 2022. PMID: 36128222 Free PMC article.
-
Associations between co-medications and survival in ALS-a cohort study from Austria.J Neurol. 2015 Jul;262(7):1698-705. doi: 10.1007/s00415-015-7767-7. Epub 2015 May 10. J Neurol. 2015. PMID: 25957641
-
Is distal motor and/or sensory demyelination a distinctive feature of anti-MAG neuropathy?J Neurol. 2016 Sep;263(9):1761-70. doi: 10.1007/s00415-016-8187-z. Epub 2016 Jun 17. J Neurol. 2016. PMID: 27314957
-
A randomized trial of mexiletine in ALS: Safety and effects on muscle cramps and progression.Neurology. 2016 Apr 19;86(16):1474-81. doi: 10.1212/WNL.0000000000002507. Epub 2016 Feb 24. Neurology. 2016. PMID: 26911633 Free PMC article. Clinical Trial.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
