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. 1972 Sep;12(1):121-32.

Differences in immune elimination in inbred mice. The role of low affinity antibody

J H Alpers, M W Steward, J F Soothill

Differences in immune elimination in inbred mice. The role of low affinity antibody

J H Alpers et al. Clin Exp Immunol. 1972 Sep.

Abstract

The rate of elimination of soluble protein antigen injected intravenously differs in different inbred strains of mice previously immunized to the antigen. This difference is apparently related to the affinity of the antibody they produce. Animals producing high affinity antibody eliminate antigen more effectively than those producing low affinity antibody. Passive transfer of antibody shows that the difference of antigen elimination is a property of the antibody, rather than the cellular mechanisms involved. The immunopathological significance of these findings is discussed.

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References

    1. J Immunol. 1970 Dec;105(6):1493-500 - PubMed
    1. N Engl J Med. 1969 Apr 17;280(16):878-84 - PubMed
    1. Immunology. 1972 May;22(5):747-56 - PubMed
    1. J Immunol. 1965 Dec;95(6):1067-73 - PubMed
    1. Nature. 1958 Jul 5;182(4627):53 - PubMed

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