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. 1979 Oct;101(4):407-12.
doi: 10.1111/j.1365-2133.1979.tb00018.x.

Studies on the plasma membrane of normal and psoriatic keratinocytes. I. Preparation of material and morphological characterization

J M Gommans, M Bergers, P E van Erp, J J van den Hurk, P D Mier, H Roelfzema

Studies on the plasma membrane of normal and psoriatic keratinocytes. I. Preparation of material and morphological characterization

J M Gommans et al. Br J Dermatol. 1979 Oct.

Abstract

A method is described for the preparation of isolated keratinocytes suitable for subsequent biochemical studies. Scanning electron microscopy showed that the maturation process is accompanied by an increase in cell size and a shortening and eventual loss of microvilli. Psoriatic keratinocytes are distinguishable by exhibiting longer microvilli at all levels of maturation.

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