[Intracellular and extracellular alkaloids of Penicillium roqueforti]
[Article in
Russian]
- PMID: 508873
Item in Clipboard
[Intracellular and extracellular alkaloids of Penicillium roqueforti]
[Article in
Russian]
Biokhimiia.
1979 Sep.
Abstract
The alkaloid composition of mycelium and culture liquid filtrate of the fungus Penicillium roqueforti IBPM-F-141 was studied. The new metabolite--3,12-dihydroroquefortine, a derivative of roquefortine, the main component of the alkaloid fraction of this culture, has been isolated for the first time. The structure of 3,12-dihydroroquefortine was determined by chemical and physico-chemical methods. In addition to roquefortine and 3,12-dihydroroquefortine, representatives of a new alkaloid group, the clavine alkaloids, e. g. isofumigaclavine A, isofumigaclavine B and festuclavine, were also isolated and identified. The data on the content of these compounds in mycelium and culture medium are presented.
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