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. 1971 Jun;42(2):311-3.
doi: 10.1111/j.1476-5381.1971.tb07115.x.

Further studies on the effect of ageing on beta-adrenoceptor activity of rat aorta

J H Fleisch

Further studies on the effect of ageing on beta-adrenoceptor activity of rat aorta

J H Fleisch. Br J Pharmacol. 1971 Jun.

Abstract

beta-Adrenoceptor activity of rat thoracic aorta decreased with the increasing age of the animal. The ability of aortas to relax to isoprenaline was completely lost when rats were 3-6 months old, depending on the source and strain of animals. NaNO(2), however, completely relaxed aortic tissue from animals of all ages tested.

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References

    1. Circ Res. 1970 Feb;26(2):151-62 - PubMed
    1. J Pharmacol Exp Ther. 1953 Jun;108(2):129-43 - PubMed

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