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. 1979;24(4):217-23.
doi: 10.1159/000131383.

Regional mapping of the gene for human UDPGal 4-epimerase on chromosome 1 in mouse-human hybrids

Regional mapping of the gene for human UDPGal 4-epimerase on chromosome 1 in mouse-human hybrids

M S Lin et al. Cytogenet Cell Genet. 1979.

Abstract

Somatic cell hybrids between mouse and human cells containing two different reciprocal translocations involving human chromosome 1, 46,X,t(1;X)(q12;q26) and 47,XX,+21,t(1;17)(p32;p13), were studied for the expression of human uridine diphosphate galactose 4-epimerase (UDPGal 4-epimerase, E.C. 5.1.3.2) by starch-gel electrophoresis. Analysis of the hybrid clones for the expression of the enzyme and the presence of the translocation chromosome 1 has permitted the assignment of the gene for human UDPGal 4-epimerase to the pter yields p32 region of chromosome 1.

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