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. 1971 Aug;3(5772):462-4.
doi: 10.1136/bmj.3.5772.462.

Amenorrhoea, galactorrhoea, and primary hypothyroidism with high circulating levels of prolactin

C R Edwards, I A Forsyth, G M Besser

Amenorrhoea, galactorrhoea, and primary hypothyroidism with high circulating levels of prolactin

C R Edwards et al. Br Med J. 1971 Aug.

Abstract

A 22-year-old woman with primary hypothyroidism developed amenorrhoea and galactorrhoea during oral contraceptive therapy. Investigation showed high levels of circulating prolactin which rose in response to insulin-induced hypoglycaemia and were suppressed by an oral glucose load. After treatment with thyroxine normal periods returned, the galactorrhoea improved, and the prolactin levels fell to undetectable levels. The results of the prolactin and human growth hormone assays confirm that it is possible to distinguish between human growth hormone and human prolactin.

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