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. 1971 Jun;25(2):270-5.
doi: 10.1038/bjc.1971.33.

A new anti-oestrogenic agent in late breast cancer. An early clinical appraisal of ICI46474

M P Cole, C T Jones, I D Todd
Free PMC article

A new anti-oestrogenic agent in late breast cancer. An early clinical appraisal of ICI46474

M P Cole et al. Br J Cancer. 1971 Jun.
Free PMC article

Abstract

An introductory clinical trial of the anti-oestrogenic agent IC146474 in late or recurrent carcinoma of the breast is described.Forty-six patients have been treated, of whom 10 have shown a good response. This is of the same order as that seen with oestrogens and androgens.The particular advantage of this drug is the low incidence of troublesome side effects.

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References

    1. Endocrinology. 1970 Sep;87(3):542-51 - PubMed
    1. Br Med J. 1971 Jan 16;1(5741):152-4 - PubMed