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Comparative Study
. 1979 Nov;32(11):1180-3.
doi: 10.1136/jcp.32.11.1180.

A sensitive single reverse passive haemagglutination test for detecting both HBsAg and anti-HBs

J A Barbara, P J Harrison, D R Howell, T E Cleghorn, D S Dane, M Briggs, C H Cameron
Comparative Study

A sensitive single reverse passive haemagglutination test for detecting both HBsAg and anti-HBs

J A Barbara et al. J Clin Pathol. 1979 Nov.

Abstract

A trial of a modified reverse passive haemagglutination test for HBsAg using a 0.1% cell suspension instead of the recommended 1% showed an approximately eight-fold increase in detection sensitivity. The test can be performed within 30 minutes and lends itself to mass screening techniques. Confirmation tests can be done using the 0.1% method. In addition, the same serological plates and cells used for HBsAg screening can then be used to screen for high-titre anti-HBs. This makes the overall screening for both HBsAg and high-titre anti-HBs donors cheap and convenient.

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References

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