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. 1971 Aug;64(2):295-304.

Target cell destruction in vitro by concanavalin A-stimulated lymphoid cells

H J Schwartz, F Wilson

Target cell destruction in vitro by concanavalin A-stimulated lymphoid cells

H J Schwartz et al. Am J Pathol. 1971 Aug.

Abstract

Guinea pig lymphoid cells obtained from lymph nodes and spleens of nonimmune animals are cytotoxic for mouse L-cell fibroblasts on incubation with concanavalin A. This effect is blocked by methyl-alpha-D-mannoside. The results indicate that this effect may be due to the release of a lymphotoxin by the concanavalin A-stimulated lymphocytes.

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References

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    1. Science. 1967 Sep 1;157(3792):1060-2 - PubMed
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