Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1971 Dec;125(3):697-701.
doi: 10.1042/bj1250697.

Cortisone-evoked decrease of acid -galactosidase, -glucuronidase, N-acetyl- -glucosaminidase and arylsulphatase in the ileum of suckling rats

O Koldovský, M Palmieri

Cortisone-evoked decrease of acid -galactosidase, -glucuronidase, N-acetyl- -glucosaminidase and arylsulphatase in the ileum of suckling rats

O Koldovský et al. Biochem J. 1971 Dec.

Abstract

Changes of activity of intestinal acid beta-galactosidase, beta-glucuronidase, N-acetyl-beta-glucosaminidase and arylsulphatase were studied in suckling rats treated with cortisone (5mg/100g body wt. daily, started on day 9 postnatally) and compared with changes in control animals. Specific activities were not changed within the first 72h, but all enzymes decreased similarly 96h after the first injection. Total activities per ileum and animal were not changed within the first 48h, but within 72h a significant decrease was observed. Calculation of the rate of decrease of the hydrolases studied in cortisone-treated animals shows that it proceeds faster than the rate of renewal of enterocytes in this period.

PubMed Disclaimer

References

    1. Nature. 1966 Dec 17;212(5068):1389-90 - PubMed
    1. Can J Biochem. 1965 Feb;43:173-8 - PubMed
    1. Annu Rev Biochem. 1970;39:929-76 - PubMed
    1. Proc Natl Acad Sci U S A. 1963 Nov;50:912-8 - PubMed
    1. Anal Biochem. 1969 Mar;27(3):409-18 - PubMed