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. 1971 Nov;4(5):541-5.
doi: 10.1128/iai.4.5.541-545.1971.

Product of Staphylococcus aureus responsible for the scalded-skin syndrome

F A Kapral, M M Miller

Product of Staphylococcus aureus responsible for the scalded-skin syndrome

F A Kapral et al. Infect Immun. 1971 Nov.

Abstract

Certain Staphylococcus aureus strains of phage group 2 produced a protein distinct from the alpha and delta toxins which was capable of causing generalized exfoliation in neonatal mice and presumably is responsible for the scalded-skin syndrome in humans. This protein, named "exfoliatin," was purified and found to have a molecular weight of approximately 24,000. Exfoliatin was acid-labile, rather heat-stabile, and antigenic.

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References

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    1. Lancet. 1960 Dec 3;2(7162):1227-9 - PubMed
    1. Arch Dermatol. 1967 Apr;95(4):359-69 - PubMed
    1. J Gen Microbiol. 1963 Mar;30:455-68 - PubMed
    1. Infect Immun. 1971 Mar;3(3):449-65 - PubMed

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