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Comparative Study
. 1971 Jul;22(1):93-5.
doi: 10.1128/am.22.1.93-95.1971.

In vitro sensitivity of Torulopsis glabrata to amphotericin B, 5-fluorocytosine, and clotrimazole (Bay 5097)

M I Marks, P Steer, T C Eickhoff
Comparative Study

In vitro sensitivity of Torulopsis glabrata to amphotericin B, 5-fluorocytosine, and clotrimazole (Bay 5097)

M I Marks et al. Appl Microbiol. 1971 Jul.

Abstract

Thirty-five strains of Torulopsis glabrata were tested by a tube dilution method for their susceptibility to amphotericin B, 5-fluorocytosine, and clotrimazole (Bay 5097). Amphotericin B was the most active in vitro, inhibiting all strains at a concentration of 1 mug/ml and killing all strains at 2 mug/ml. 5-Fluorocytosine inhibited over 80% of strains at 0.24 mug/ml, but three strains required >/=7.8 mug/ml for killing. A concentration of 2 mug of clotrimazole per ml inhibited less than 50% of strains, and 8 mug/ml killed only 10% of strains. Most strains of T. glabrata were killed by therapeutically achievable concentrations of amphotericin B and 5-fluorocytosine, but not clotrimazole.

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References

    1. JAMA. 1968 Mar 4;203(10):835-7 - PubMed
    1. Appl Microbiol. 1969 Jun;17(6):871-7 - PubMed
    1. Appl Microbiol. 1970 Jan;19(1):184-5 - PubMed
    1. Antimicrob Agents Chemother (Bethesda). 1969;9:271-4 - PubMed
    1. Antimicrob Agents Chemother (Bethesda). 1970;10:491-3 - PubMed

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