Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Sep 15;182(3):885-7.
doi: 10.1042/bj1820885.

N-formyl-L-methionine deformylase activity in human leucocytes and platelets

S K Ackerman, S D Douglas

N-formyl-L-methionine deformylase activity in human leucocytes and platelets

S K Ackerman et al. Biochem J. .

Abstract

Extracts of human neutrophils, lymphocytes and platelets enzymically deformylate N-formyl-L-methionine. Enzyme activity is stimulated by Co2+, inhibited by bivalent-cation chelators and unaffected by inhibitors of serine, thiol and carboxyl proteinases. Leucocyte or platelet N-formylmethionine deformylase may be important in modulation of neutrophil responses to chemoattractant formylmethionyl peptides or similar compounds.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. J Biol Chem. 1952 Jan;194(1):455-70 - PubMed
    1. Biochem Biophys Res Commun. 1977 Jul 11;77(1):237-44 - PubMed
    1. J Immunol. 1975 Jun;114(6):1831-7 - PubMed
    1. J Mol Biol. 1968 May 14;33(3):571-89 - PubMed
    1. J Mol Biol. 1967 Sep 28;28(3):423-33 - PubMed

Publication types