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Comparative Study
. 1979 Dec 14;581(2):365-70.
doi: 10.1016/0005-2795(79)90258-7.

Interaction of alpha-actinin, filamin and tropomyosin with F-actin

Comparative Study

Interaction of alpha-actinin, filamin and tropomyosin with F-actin

M G Zeece et al. Biochim Biophys Acta. .

Abstract

The abilities of alpha-actinin, filamin and tropomyosin to bind F-actin were examined by cosedimentation experiments. Results indicated that smooth muscle alpha-actinin and filamin can bind to actin filaments simultaneously with little evidence of competition. In contrast, tropomyosin exhibits marked competition with either filamin or alpha-actinin for sites on actin filaments.

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