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. 1975 Oct;16(4):991-9.
doi: 10.1128/JVI.16.4.991-999.1975.

Variants of N-tropic leukemia virus derived from BALB/c mice

N Hopkins, P Jolicoeur

Variants of N-tropic leukemia virus derived from BALB/c mice

N Hopkins et al. J Virol. 1975 Oct.

Abstract

Clonal lines derived from cultures of NIH/3T3 cells infected with N-tropic leukemia virus from BALB/c mice differ in the amount and type of N-tropic virus they produce. Three biologically distinguishable N-tropic viruses were found: the large XC plaque-forming virus of hartley et al. (1969) (LP-N), A SMALL XC plaque-forming virus (sp-n), and a non-plaque-forming virus (NP-N). SP-N and NP-N are less infectious than LP-N. Upon prolonged passage in NIH/3T3 cells NP-N gives rise to highly infectious LP-N.

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References

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