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. 1979 Dec 15;35(12):1631-2.
doi: 10.1007/BF01953235.

Thioridazine and EKG anomalies

B Hine, L J Traficante, G Sakalis, S Gershon

Thioridazine and EKG anomalies

B Hine et al. Experientia. .

Abstract

Acute i.v. infusion but not daily oral administration of thioridazine-HCl in the dog produced EKG anomalies similar to those reported in psychiatric patients taking this drug. Lack of EKG effects after thioridazine-5-sulfoxide infusion and presence of anomalies after thioridazine at equivalent doses suggests further evaluation of the relationship between reported plasma levels of thioridazine and its ring-sulfoxide in association with EKG changes.

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References

    1. Can Med Assoc J. 1963 Sep 14;89:546-54 - PubMed
    1. Can Med Assoc J. 1964 Sep 5;91:537-40 - PubMed
    1. Commun Psychopharmacol. 1977;1(4):407-19 - PubMed
    1. Proc West Pharmacol Soc. 1978;21:311-2 - PubMed