Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1968 Oct;22(4):767-78.
doi: 10.1002/1097-0142(196810)22:4<767::aid-cncr2820220412>3.0.co;2-7.

Clinical radiation pathology as applied to curative radiotherapy

P Rubin, G W Casarett

Clinical radiation pathology as applied to curative radiotherapy

P Rubin et al. Cancer. 1968 Oct.

Abstract

The value of radiation pathology in understanding the radiation effects in normal tissues and tumors is stressed in developing curative radiotherapy. A theory of cell radiosensitivity is presented based on cellular proliferation, differentiation and life span. From this base, concepts of tissue and organ radiosensitivity are developed utilizing the knowledge of tissue organization, cell kinetics and microcirculation. Through a series of paradigmatic charts and drawings an attempt is made to explain different clinical manifestations of radiation reactions on the basis of similar histopathologic changes. Possible future directions for radiation research to explore are outlined.

PubMed Disclaimer

LinkOut - more resources