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. 1979 Oct-Dec;17(4):241-4.

Inhibition of testosterone-induced prostate growth in the rat by melatonin-free pineal extract

  • PMID: 523941

Inhibition of testosterone-induced prostate growth in the rat by melatonin-free pineal extract

E Damian et al. Endocrinologie. 1979 Oct-Dec.

Abstract

Administration of the melatonin-free pineal extract to rats concomitantly receiving testosterone propionate caused partial inhibition of the ventral prostate growth induced by testosterone. Administration of the pineal extract to rats likewise caused a statistically significant decrease in the ventral prostate weight under basal conditions. The mechanism of action is discussed.

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