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. 1975 Nov;35(11 Pt 1):3204-8.

Effect of metabolic inhibitors on the ability of tumor cells to express antigen and bind complement components C4 and C3

  • PMID: 52405

Effect of metabolic inhibitors on the ability of tumor cells to express antigen and bind complement components C4 and C3

M Segerling et al. Cancer Res. 1975 Nov.

Abstract

Metabolic inhibitors commonly used in the treatment of cancer increase the ability of antibody and complement to kill guinea pig tumor cells in vitro. No correlation was found between increased killing and changes in cell surface antigen concentration or binding of complement components C4 and C3.

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