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. 1969 Jan;62(1):171-8.
doi: 10.1073/pnas.62.1.171.

On the conformational instability of human serum low-density lipoprotein: effect of temperature

A Scanu, H Pollard, R Hirz, K Kothary

On the conformational instability of human serum low-density lipoprotein: effect of temperature

A Scanu et al. Proc Natl Acad Sci U S A. 1969 Jan.

Abstract

When examined by circular dichroism and ultraviolet spectroscopy, human serum low-density lipoprotein (LDL) and its delipidated product, apo LDL, exhibited reversible thermal changes. The more marked temperature sensitivity of apo LDL as compared to LDL was taken to support a constraining role by lipids on the observed structural instability of the apoprotein.

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References

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