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. 1969 Feb;62(2):468-74.
doi: 10.1073/pnas.62.2.468.

A mutant of yeast apparently defective in the initiation of protein synthesis

L H Hartwell, C S McLaughlin

A mutant of yeast apparently defective in the initiation of protein synthesis

L H Hartwell et al. Proc Natl Acad Sci U S A. 1969 Feb.

Abstract

A temperature-sensitive mutant of yeast, ts(-)187, which is apparently unable to initiate the synthesis of new polypeptide chains after a short incubation at the restrictive temperature, is described. The existence of this mutant demonstrates that in eucaryotic cells, as in procaryotic cells, there are processes unique to the initiation of polypeptide chains.

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References

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    1. Proc Natl Acad Sci U S A. 1961 Dec 15;47:2005-14 - PubMed
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