doi: 10.1073/pnas.62.4.1129.
Solubilization of particulate proteins and nonelectrolytes by chaotropic agents
- PMID: 5256411
- PMCID: PMC223624
- DOI: 10.1073/pnas.62.4.1129
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Solubilization of particulate proteins and nonelectrolytes by chaotropic agents
Proc Natl Acad Sci U S A.
1969 Apr.
Abstract
Chaotropic ions (those ions which favor the transfer of apolar groups to water) provide a highly effective means for the resolution of membranes and multicomponent enzymes and for increasing the water solubility of particular proteins and nonelectrolytes. The action of chaotropic agents is related to their effect on the structure and lipophilicity of water.
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