Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1969 Apr;62(4):1167-74.
doi: 10.1073/pnas.62.4.1167.

Location of single-strand interruptions in the DNA of bacteriophage T5

H Bujard

Location of single-strand interruptions in the DNA of bacteriophage T5

H Bujard. Proc Natl Acad Sci U S A. 1969 Apr.

Abstract

The positions of three single-strand interruptions in the DNA of phage T5(+) have been located by electron microscopy. All three interruptions were found in the same strand. Uneven base composition along the molecule is indicated by the preferential melting of certain regions. The data suggest a model according to which (1) the first-step-transfer DNA section is separated by a single-strand interruption from the rest of the phage genome, (2) the phage carries only one such section and therefore transfers the asymmetrical DNA molecule always in the same direction into the host cell, and (3) single-strand interruptions are points of preferred breakage.

PubMed Disclaimer

References

    1. Virology. 1966 Jan;28(1):11-4 - PubMed
    1. J Mol Biol. 1965 Jul;12(3):525-36 - PubMed
    1. Proc Natl Acad Sci U S A. 1965 May;53(5):969-73 - PubMed
    1. J Mol Biol. 1967 Jan 28;23(2):163-81 - PubMed
    1. Bacteriol Rev. 1968 Sep;32(3):227-42 - PubMed

LinkOut - more resources