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. 1969 Aug;63(4):1370-6.
doi: 10.1073/pnas.63.4.1370.

In vitro synthesis of different categories of specific protein by membrane-bound and free ribosomes

M C Ganoza, C A Williams

In vitro synthesis of different categories of specific protein by membrane-bound and free ribosomes

M C Ganoza et al. Proc Natl Acad Sci U S A. 1969 Aug.

Abstract

The free and membrane-bound ribosomes of hepatic cells were isolated and used to program protein synthesis in cell-free extracts. Immuno-electrophoretic and radioautographic analysis of the products showed that the membrane-bound ribosomes synthesized serum proteins, whereas ribosomes free of endoplasmic reticulum synthesized specific nonserum liver proteins. After synthesis, the serum proteins remained associated with membrane vesicles, whereas the other liver proteins were found free of cytoplasmic organelles.

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References

    1. Biochem Biophys Res Commun. 1968 Sep 30;32(6):1050-6 - PubMed
    1. Nature. 1963 Feb 2;197:430-5 - PubMed
    1. Biochem Biophys Res Commun. 1968 Jun 28;31(6):845-50 - PubMed
    1. J Mol Biol. 1965 Sep;13(2):511-20 - PubMed
    1. J Biol Chem. 1962 Apr;237:1186-9 - PubMed

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